Thyroid Functions in Psychiatric Disorders: The Low TSH Levels in Unipolar Depressive Patients
1Ataturk University Faculty of Medicine Department of Psychiatry
2Atatürk University Faculty of Medicine, Department of Physiology
3Atatürk University Faculty of Medicine, Department of Biochemistry
2Atatürk University Faculty of Medicine, Department of Physiology
3Atatürk University Faculty of Medicine, Department of Biochemistry
Dusunen Adam Journal of Psychiatry and Neurological Sciences 1994; 7(1): 27-30
Abstract
The study was carried out in 92 psychiatric inpatients (39 schizophrenia, 22 unipola ı- depressive and 17 bipolar manic affective disorders, 14 paranoid disorders) and 54 healthy subjects. TSH levels were significantly higher in schizophrenics than those in unipolar group (t=3 .59, p<0.01). There was a statistically significant difference in TSH concentrations in unipolar group when compared to controls (t=3 .88, p<0.01). Low plasma TSH level may be due to supressive effect of increased circulating cortisol in depressive disorders.
Keywords: Thyroid function, psychiatric disorders
